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FAK-p38 signaling serves as a potential target for reverting matrix stiffness-modulated liver sinusoidal endothelial cell defenestration 期刊论文
BIOMATERIALS, 2024, 卷号: 305, 页码: 17
Authors:  Zhang XY(张晓宇);  Li PW(李培文);  Zhou J(周瑾);  Zhang ZL(张子良);  Wu H(吴欢);  Shu XY(舒芯钰);  Li W(李旺);  Wu Y(武亿);  Du Y(杜宇);  Lv DY(吕东媛);  Lv SQ(吕守芹);  Li N(李宁);  Long M(龙勉)
Favorite  |  View/Download:27/0  |  Submit date:2024/04/02
Liver sinusoidal endothelial cells  Fenestrae  Liver fibrosis  Cytoskeleton remodeling  FAK  MAPK  
Biomechanics in liver regeneration after partial hepatectomy 期刊论文
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY, 2023, 卷号: 11, 页码: 1165651
Authors:  Wu Y(武亿);  Li N(李宁);  Shu XY(舒芯钰);  Li W(李旺);  Zhang XY(张晓宇);  Lv DY(吕东媛);  Long M(龙勉)
Adobe PDF(2065Kb)  |  Favorite  |  View/Download:73/0  |  Submit date:2023/07/17
liver regeneration  partial hepatectomy  hemodynamics  mechanical loading  mechanotransduction  
Hepatic differentiation of human embryonic stem cells by coupling substrate stiffness and microtopography 期刊论文
BIOMATERIALS SCIENCE, 2021, 页码: 15
Authors:  Luo CH(罗春花);  Lv DY(吕东媛);  Zheng L(郑鲁);  Zhang F(张帆);  Zhang X(张潇);  Lv SQ(吕守芹);  Zhang C(张晨);  Jia Xiaohua;  Shu XY(舒芯钰);  Li PW(李培文);  Li Z(李展);  Long M(龙勉)
Adobe PDF(7505Kb)  |  Favorite  |  View/Download:319/166  |  Submit date:2021/05/17
Mechanotransduction of liver sinusoidal endothelial cells under varied mechanical stimuli 期刊论文
ACTA MECHANICA SINICA, 2021, 页码: 17
Authors:  Shu XY(舒芯钰);  Li N(李宁);  Wu Y(武亿);  Li W(李旺);  Zhang XY(张晓宇);  Li PW(李培文);  Lv DY(吕东媛);  Lv SQ(吕守芹);  Long M(龙勉)
Adobe PDF(1359Kb)  |  Favorite  |  View/Download:400/112  |  Submit date:2021/05/06
Liver sinusoidal endothelial cell  Shear stress  Mechanical stretch  Extracellular matrix  Stiffness  
Regulation of hepatic differentiation of human embryonic stem cells by calcium silicate extracts for liver injury repairing 期刊论文
Applied Materials Today, 2020, 卷号: 20, 页码: 100730
Authors:  Zheng L;  Lv DY(吕东媛);  Zhang F;  Xing M;  Wang XY;  Jia XH;  Shu XY;  Li PW(李培文);  Lv SQ(吕守芹);  Chang J;  Long M(龙勉)
Adobe PDF(3951Kb)  |  Favorite  |  View/Download:207/76  |  Submit date:2021/01/29
Human embryonic stem cells  Hepatic differentiation  Hepatocyte-like cells  Calcium silicate extracts  Liver injury repair  
Flow-enhanced priming of hESCs through H2B acetylation and chromatin decondensation 期刊论文
STEM CELL RESEARCH & THERAPY, 2019, 卷号: 10, 期号: 1, 页码: 16
Authors:  Wang JW(王家文);  Wu Y(武亿);  Zhang X(张潇);  Zhang F(张帆);  Lv DY(吕东媛);  Shang GB(上官冰);  Gao YX(高宇欣);  Long M(龙勉)
View  |  Adobe PDF(2406Kb)  |  Favorite  |  View/Download:227/71  |  Submit date:2020/03/11
Embryonic stem cell  Fluid shear mechanomics  Nuclear spreading  Histone acetylation  Chromatin decondensation  
Cell Growth and Differentiation Under Microgravity 图书章节
2019
Authors:  Sun SJ(孙树津);  Wang CZ(王成之);  Li N(李宁);  Lv DY(吕东媛);  Chen Q(陈琴);  Long M(龙勉)
View  |  Adobe PDF(1205Kb)  |  Favorite  |  View/Download:200/45  |  Submit date:2019/12/26
Microgravity-induced hepatogenic differentiation of rBMSCs on board the SJ-10 satellite 期刊论文
FASEB JOURNAL, 2019, 卷号: 33, 期号: 3, 页码: 4273-4286
Authors:  Lv DY(吕东媛);  Sun SJ(孙树津);  Zhang F(张帆);  Luo CH(罗春花);  Zheng L;  Wu Y(武毅);  Li N(李宁);  Zhang C;  Wang CZ;  Chen Q;  Long M(龙勉)
View  |  Adobe PDF(3477Kb)  |  Favorite  |  View/Download:322/100  |  Submit date:2019/04/11
mesenchymal stem cells  mechanotransduction  hepatocyte  signaling pathway  
Microgravity-Induced Alterations of Inflammation-Related Mechanotransduction in Endothelial Cells on Board SJ-10 Satellite 期刊论文
FRONTIERS IN PHYSIOLOGY, 2018, 卷号: 9, 页码: 1025
Authors:  Li N(李宁);  Wang CZ(王成之);  Sun SJ(孙树津);  Zhang C(张晨);  Lv DY(吕东媛);  Chen Q(陈琴);  Long M(龙勉)
View  |  Adobe PDF(3456Kb)  |  Favorite  |  View/Download:624/424  |  Submit date:2018/10/19
Microgravity  Sj-10 Satellite  Endothelial Cells  Adhesive Molecules  Cytoskeleton  Mechanotransduction  Nitric Oxide  Exosome Rna  
Theoretical modeling of mechanical homeostasis of a mammalian cell under gravity-directed vector 期刊论文
BIOMECHANICS AND MODELING IN MECHANOBIOLOGY, 2018, 卷号: 17, 期号: 1, 页码: 191-203
Authors:  Zhou LW(周吕文);  Zhang C(张晨);  Zhang F(张芳);  Lv SQ(吕守芹);  Sun SJ(孙树津);  Lv DY(吕东媛);  Long M(龙勉)
View  |  Adobe PDF(860Kb)  |  Favorite  |  View/Download:421/226  |  Submit date:2018/10/30
Gravity directed  Mechanosensing  Nucleus translocation  Cytoskeletal remodeling  FAC reorganization