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A Novel Human Antibody, HF, against HER2/erb-B2 Obtained by a Computer-Aided Antibody Design Method 期刊论文
ENGINEERING, 2021, 卷号: 7, 期号: 11, 页码: 1566-1576
作者:  Qiao, Chunxia;  Lv, Ming;  Li, Xinying;  Lang, Xiaoling;  Lv SQ(吕守芹);  Long M(龙勉);  Li, Yan;  Geng, Shusheng;  Lin, Zhou;  Shen, Beifen;  Feng, Jiannan
Adobe PDF(4174Kb)  |  收藏  |  浏览/下载：182/30  |  提交时间：2022/02/17
HER2/erb-B2  Human antibody  Computer-aided design  
Multi-scale molecular dynamics simulations and applications on mechanosensitive proteins of integrins* 期刊论文
CHINESE PHYSICS B, 2021, 卷号: 30, 期号: 3, 页码: 8
作者:  Lv SQ(吕守芹);  Ding QH(丁奇寒);  Zhang MK(张明坤);  Long M(龙勉)
Adobe PDF(834Kb)  |  收藏  |  浏览/下载：264/83  |  提交时间：2021/04/19
molecular dynamics simulations  mechanosensitive protein  allosteric dynamics  integrin  
Regulation of hepatic differentiation of human embryonic stem cells by calcium silicate extracts for liver injury repairing 期刊论文
Applied Materials Today, 2020, 卷号: 20, 页码: 100730
作者:  Zheng L;  Lv DY(吕东媛);  Zhang F;  Xing M;  Wang XY;  Jia XH;  Shu XY;  Li PW(李培文);  Lv SQ(吕守芹);  Chang J;  Long M(龙勉)
Adobe PDF(3951Kb)  |  收藏  |  浏览/下载：186/70  |  提交时间：2021/01/29
Human embryonic stem cells  Hepatic differentiation  Hepatocyte-like cells  Calcium silicate extracts  Liver injury repair  
Mechanical Strength and Structural Basis of beta(2) Integrin to Mediate Neutrophil Accumulation on Liver Sinusoidal Endothelial Cells: A Study Using Atomic Force Microscopy and Molecular Dynamics Simulations 期刊论文
CMES-COMPUTER MODELING IN ENGINEERING & SCIENCES, 2018, 卷号: 116, 期号: 2, 页码: 263-279
作者:  Li N(李宁);  Zhang X(张潇);  Li PW;  Yang H;  Tong CF;  Lv SQ(吕守芹);  Zhang Y(章燕);  Ye ZY;  Pan J;  Long M(龙勉)
浏览  |  Adobe PDF(865Kb)  |  收藏  |  浏览/下载：387/188  |  提交时间：2018/10/30
Liver sinusoidal endothelial cells  neutrophils  beta(2) integrin  shear flow  mechanical strength  
Mimicking liver sinusoidal structures and functions using a 3D-configured microfluidic chip 期刊论文
LAB ON A CHIP, 2017, 卷号: 17, 期号: 5, 页码: 782-794
作者:  Du Y(杜宇);  Li N(李宁);  Yang H(杨浩);  Luo CH(罗春花);  Gong YX;  Tong CF(佟春芳);  Gao YX(高宇新);  Lv SQ(吕守芹);  Long M(龙勉);  Long, M (reprint author), Chinese Acad Sci, Key Lab Micrograv, Natl Micrograv Lab, Ctr Biomech & Bioengn, Beijing 100190, Peoples R China.;  Long, M (reprint author), Chinese Acad Sci, Beijing Key Lab Engn Construct & Mech, Inst Mech, Beijing 100190, Peoples R China.;  Long, M (reprint author), Univ Chinese Acad Sci, Sch Engn Sci, Beijing 100049, Peoples R China.
浏览  |  Adobe PDF(6728Kb)  |  收藏  |  浏览/下载：754/489  |  提交时间：2017/07/24
Identification of the Conformational transition pathway in PIP2 Opening Kir Channels 期刊论文
SCIENTIFIC REPORTS, 2015, 卷号: 5, 页码: 11289
作者:  Li JW;  Lv SQ(吕守芹);  Liu YZ;  Pang CL;  Chen YF;  Zhang SH;  Yu H;  Long M(龙勉);  Zhang HL;  Logothetis DE;  Zhan Y;  An HL;  An, HL (reprint author), Hebei Univ Technol, Inst Biophys, Sch Sci, Key Lab Mol Biophys, Tianjin 300401, Hebei Province, Peoples R China.
浏览  |  Adobe PDF(2141Kb)  |  收藏  |  浏览/下载：465/113  |  提交时间：2015/07/21
The impact of N-terminal phosphorylation on LHCII conformation in state transition 期刊论文
Acta Mechanica Sinica, 2014, 卷号: 30, 期号: 3, 页码: 447-456
作者:  Ding JH(丁锦鸿);  Li N(李宁);  Wang ML;  Zhang Y(章燕);  Lv SQ(吕守芹);  Long M(龙勉);  Lu, SQ (reprint author), Chinese Acad Sci, Natl Micrograv Lab, Key Lab Micrograv, Beijing 100190, Peoples R China.
浏览  |  Adobe PDF(746Kb)  |  收藏  |  浏览/下载：684/147  |  提交时间：2014/09/03
State Transition  Lhcii  Phosphorylation  Conformation  
Distinct binding affinities of Mac-1 and LFA-1 in neutrophil activation 期刊论文
JOURNAL OF IMMUNOLOGY, 2013, 卷号: 190, 期号: 8, 页码: 4371-4381
作者:  Li N(李宁);  Mao DB(毛德斌);  Lv SQ(吕守芹);  Tong CF(佟春芳);  Zhang Y(章燕);  Long M(龙勉);  Long, M (reprint author), Chinese Acad Sci, Inst Mech, Natl Micrograv Lab, Key Lab Micrograv, 15 North 4th Ring Rd, Beijing 100190, Peoples R China.
Adobe PDF(777Kb)  |  收藏  |  浏览/下载：1405/355  |  提交时间：2013/05/21
分子动力学模拟与分子生物力学 期刊论文
生物物理学报, 2012, 卷号: 28, 期号: 1, 页码: 6-14
作者:  吕守芹;  龙勉
Adobe PDF(378Kb)  |  收藏  |  浏览/下载：2726/572  |  提交时间：2013/01/16
分子动力学模拟  分子生物力学  微观结构动力学  结构-功能关系  
Conformational Stability Analyses of Alpha Subunit I Domain of LFA-1 and Mac-1 期刊论文
PLOS One, 2011, 卷号: 6, 期号: 8, 页码: e24188
作者:  Mao DB(毛德斌);  Lv SQ(吕守芹);  Li N(李宁);  Zhang Y(章燕);  Long M(龙勉);  Mao, DB (reprint author), Chinese Acad Sci, Inst Mech, Key Lab Micrograv, Beijing 100080, Peoples R China
Adobe PDF(818Kb)  |  收藏  |  浏览/下载：1274/289  |  提交时间：2012/04/01
A-domain  Molecular-dynamics  Structural Basis  Integrin Activation  Crystal-structure  Cell-adhesion  T-cell  Neutrophils  Affinity  Migration