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Cell senescence alters responses of porcine trabecular meshwork cells to shear stress 期刊论文
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY, 2022, 卷号: 10, 页码: 14
作者:  Du, Ruotian;  Li, Dongyan;  Zhu, Meng;  Zheng, Lisha;  Ren, Keli;  Han, Dong;  Li L(李龙);  Ji, Jing;  Fan, Yubo
Adobe PDF(2336Kb)  |  收藏  |  浏览/下载:196/31  |  提交时间:2023/01/12
shear stress  senescence  trabecular meshwork cell  glaucoma  mechanobiology  
Matrix stiffness exacerbates the proinflammatory responses of vascular smooth muscle cell through the DDR1-DNMT1 mechanotransduction axis 期刊论文
BIOACTIVE MATERIALS, 2022, 卷号: 17, 页码: 406-424
作者:  Wang, Jin;  Xie, Si-an;  Li N(李宁);  Zhang, Tao;  Yao, Weijuan;  Zhao, Hucheng;  Pang, Wei;  Han, Lili;  Liu, Jiayu;  Zhou, Jing
Adobe PDF(21819Kb)  |  收藏  |  浏览/下载:276/23  |  提交时间:2022/06/10
Matrix stiffness  Inflammation  DDR1  DNMT1  Mechanotransduction  
Material properties of phase-separated TFEB condensates regulate the autophagy-lysosome pathway 期刊论文
JOURNAL OF CELL BIOLOGY, 2022, 卷号: 221, 期号: 5, 页码: 27
作者:  Wang,Zheng;  Chen,Di;  Guan DS(关东石);  Liang,Xiaobo;  Xue,Jianfeng;  Zhao HY(赵宏宇);  Song,Guangtao;  Lou,Jizhong;  He,Yan;  Zhang,Hong
Adobe PDF(7881Kb)  |  收藏  |  浏览/下载:109/20  |  提交时间:2022/11/14
E-selectin negatively regulates polymorphonuclear neutrophil transmigration through altered endothelial junction integrity 期刊论文
FASEB JOURNAL, 2021, 卷号: 35, 期号: 5, 页码: 15
作者:  Huang DD(黄丹丹);  Ding QH(丁奇寒);  Chen SB(陈深宝);  Lv SQ(吕守芹);  Zhang Y(章燕);  Long M(龙勉)
Adobe PDF(2008Kb)  |  收藏  |  浏览/下载:257/75  |  提交时间:2021/08/03
cytoskeletal remodeling  endothelial integrity  E-selectin  neutrophil  transmigration  
Multi-scale molecular dynamics simulations and applications on mechanosensitive proteins of integrins* 期刊论文
CHINESE PHYSICS B, 2021, 卷号: 30, 期号: 3, 页码: 8
作者:  Lv SQ(吕守芹);  Ding QH(丁奇寒);  Zhang MK(张明坤);  Long M(龙勉)
Adobe PDF(834Kb)  |  收藏  |  浏览/下载:267/84  |  提交时间:2021/04/19
molecular dynamics simulations  mechanosensitive protein  allosteric dynamics  integrin  
CD44-配体相互作用的生物力学与功能调控 期刊论文
力学学报, 2021, 卷号: 53, 期号: 02, 页码: 539-553
作者:  李林达;  丁奇寒;  陈深宝;  吕守芹;  龙勉;  郭兴明
Adobe PDF(796Kb)  |  收藏  |  浏览/下载:376/88  |  提交时间:2021/04/19
CD44  选择素  透明质酸  细胞粘附  力学调控  炎症反应  
Mechanomics analysis of hESCs under combined mechanical shear, stretch, and compression 期刊论文
BIOMECHANICS AND MODELING IN MECHANOBIOLOGY, 2020, 页码: 18
作者:  Zhang F(张帆);  Wang JW(王家文);  Lv DY(吕东媛);  Zheng L(郑璐);  Shang GB(上官冰);  Gao YX(高宇欣);  Wu Y(武亿);  Long M(龙勉)
Adobe PDF(8050Kb)  |  收藏  |  浏览/下载:310/167  |  提交时间:2020/10/23
Mechanomics  hESCs  iTRAQ  GSEA  WGCNA  
Biomechanical stress regulates mammalian tooth replacement via the integrin beta 1-RUNX2-Wnt pathway 期刊论文
EMBO JOURNAL, 2020, 卷号: 39, 期号: 3, 页码: 19
作者:  Wu XS;  Hu JR(胡锦荣);  Li GQ;  Li Y;  Li Y;  Zhang J;  Wang F;  Li A;  Hu L;  Fan ZP;  Lv SQ(吕守芹);  Ding G;  Zhang CM;  Wang JS;  Long M(龙勉);  Wang SL
Adobe PDF(7490Kb)  |  收藏  |  浏览/下载:238/64  |  提交时间:2020/03/11
biomechanics  organ replacement  stress  Wnt signaling  
Flow-enhanced priming of hESCs through H2B acetylation and chromatin decondensation 期刊论文
STEM CELL RESEARCH & THERAPY, 2019, 卷号: 10, 期号: 1, 页码: 16
作者:  Wang JW(王家文);  Wu Y(武亿);  Zhang X(张潇);  Zhang F(张帆);  Lv DY(吕东媛);  Shang GB(上官冰);  Gao YX(高宇欣);  Long M(龙勉)
浏览  |  Adobe PDF(2406Kb)  |  收藏  |  浏览/下载:218/68  |  提交时间:2020/03/11
Embryonic stem cell  Fluid shear mechanomics  Nuclear spreading  Histone acetylation  Chromatin decondensation  
Mechanical Point Loading Induces Cortex Stiffening and Actin Reorganization 期刊论文
BIOPHYSICAL JOURNAL, 2019, 卷号: 117, 期号: 8, 页码: 1405-1418
作者:  Hu JR(胡锦荣);  Chen SB(陈深宝);  Hu WH(胡文慧);  Lv SQ(吕守芹);  Long M(龙勉)
浏览  |  Adobe PDF(4950Kb)  |  收藏  |  浏览/下载:383/73  |  提交时间:2019/11/26