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FAK-p38 signaling serves as a potential target for reverting matrix stiffness-modulated liver sinusoidal endothelial cell defenestration 期刊论文
BIOMATERIALS, 2024, 卷号: 305, 页码: 17
作者:  Zhang XY(张晓宇);  Li PW(李培文);  Zhou J(周瑾);  Zhang ZL(张子良);  Wu H(吴欢);  Shu XY(舒芯钰);  Li W(李旺);  Wu Y(武亿);  Du Y(杜宇);  Lv DY(吕东媛);  Lv SQ(吕守芹);  Li N(李宁);  Long M(龙勉)
收藏  |  浏览/下载:7/0  |  提交时间:2024/04/02
Liver sinusoidal endothelial cells  Fenestrae  Liver fibrosis  Cytoskeleton remodeling  FAK  MAPK  
Direct mechanical exposure initiates hepatocyte proliferation 期刊论文
JHEP REPORTS, 2023, 卷号: 5, 期号: 12, 页码: 13
作者:  Li, Wang;  Wu Y(武亿);  Hu, Wenhui;  Zhou J(周瑾);  Shu XY(舒芯钰);  Zhang XY(张晓宇);  Zhang, Ziliang;  Wu, Huan;  Du, Yu;  Lv DY(吕东媛);  Lv SQ(吕守芹);  Li N(李宁);  Long M(龙勉)
Adobe PDF(3334Kb)  |  收藏  |  浏览/下载:52/0  |  提交时间:2024/01/02
Mechanotransduction  FAK  hepatic sinusoid chip  
Disturbed Flow-Facilitated Margination and Targeting of Nanodisks Protect against Atherosclerosis 期刊论文
SMALL, 2023, 卷号: 19, 期号: 2, 页码: 10.1002/smll.202204694
作者:  Zhao, ChuanRong;  Li, Jingyi;  Jiang, ZhiTong;  Zhu, JuanJuan;  Zhao, JiaNan;  Yang, QianRu;  Yao, Weijuan;  Pang, Wei;  Li N(李宁);  Yu, Miaorong;  Gan, Yong;  Zhou, Jing
Adobe PDF(4465Kb)  |  收藏  |  浏览/下载:198/75  |  提交时间:2022/12/20
atherosclerosis  decitabine  endothelial inflammation  hemodynamics  nanoparticles  
Numerical simulation of flow characteristics in a permeable liver sinusoid with leukocytes 期刊论文
BIOPHYSICAL JOURNAL, 2022, 卷号: 121, 期号: 23, 页码: 4666-4678
作者:  Chen SB(陈深宝);  Zhu, Jingchen;  Xue J(薛健);  Wang, Xiaolong;  Jing, Peng;  Zhou, Luwen;  Cui, Yuhong;  Wang, Tianhao;  Gong, Xiaobo;  Lv SQ(吕守芹);  Long M(龙勉)
Adobe PDF(3140Kb)  |  收藏  |  浏览/下载:196/63  |  提交时间:2023/02/07
Cell senescence alters responses of porcine trabecular meshwork cells to shear stress 期刊论文
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY, 2022, 卷号: 10, 页码: 14
作者:  Du, Ruotian;  Li, Dongyan;  Zhu, Meng;  Zheng, Lisha;  Ren, Keli;  Han, Dong;  Li L(李龙);  Ji, Jing;  Fan, Yubo
Adobe PDF(2336Kb)  |  收藏  |  浏览/下载:192/30  |  提交时间:2023/01/12
shear stress  senescence  trabecular meshwork cell  glaucoma  mechanobiology  
Distinct binding kinetics of E-, P- and L-selectins to CD44 期刊论文
FEBS JOURNAL, 2022, 页码: 18
作者:  Li LD(李林达);  Ding QH(丁奇寒);  Zhou J(周瑾);  Wu Y(武亿);  Zhang MK(张明坤);  Guo XM;  Long M(龙勉);  Lv SQ(吕守芹)
Adobe PDF(5539Kb)  |  收藏  |  浏览/下载:261/74  |  提交时间:2022/01/12
binding epitope  binding kinetics  CD44  selectin  
Influence of microflow on hepatic sinusoid blood flow and red blood cell deformation 期刊论文
BIOPHYSICAL JOURNAL, 2021, 卷号: 120, 期号: 21, 页码: 4859-4873
作者:  Wang, Tianhao;  Lv SQ(吕守芹);  Hao, Yinjing;  Su, Zinan;  Long M(龙勉);  Cui, Yuhong
Adobe PDF(3057Kb)  |  收藏  |  浏览/下载:185/32  |  提交时间:2022/01/12
Hepatic differentiation of human embryonic stem cells by coupling substrate stiffness and microtopography 期刊论文
BIOMATERIALS SCIENCE, 2021, 页码: 15
作者:  Luo CH(罗春花);  Lv DY(吕东媛);  Zheng L(郑鲁);  Zhang F(张帆);  Zhang X(张潇);  Lv SQ(吕守芹);  Zhang C(张晨);  Jia Xiaohua;  Shu XY(舒芯钰);  Li PW(李培文);  Li Z(李展);  Long M(龙勉)
Adobe PDF(7505Kb)  |  收藏  |  浏览/下载:294/153  |  提交时间:2021/05/17
Interplay Between Receptor-Ligand Binding and Lipid Domain Formation Depends on the Mobility of Ligands in Cell-Substrate Adhesion 期刊论文
FRONTIERS IN MOLECULAR BIOSCIENCES, 2021, 卷号: 8, 页码: 9
作者:  Li L(李龙);  Wang XH(王小环);  Wu, Helong;  Shao YF(邵颖峰);  Wu, Huaping;  Song F(宋凡)
Adobe PDF(1678Kb)  |  收藏  |  浏览/下载:248/54  |  提交时间:2021/05/31
cell adhesion  receptor-ligand binding  nanoscale lipid cluster  ligand mobility  phase separation  binding constant  
Mechanotransduction of liver sinusoidal endothelial cells under varied mechanical stimuli 期刊论文
ACTA MECHANICA SINICA, 2021, 页码: 17
作者:  Shu XY(舒芯钰);  Li N(李宁);  Wu Y(武亿);  Li W(李旺);  Zhang XY(张晓宇);  Li PW(李培文);  Lv DY(吕东媛);  Lv SQ(吕守芹);  Long M(龙勉)
Adobe PDF(1359Kb)  |  收藏  |  浏览/下载:368/101  |  提交时间:2021/05/06
Liver sinusoidal endothelial cell  Shear stress  Mechanical stretch  Extracellular matrix  Stiffness