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中国科学院力学研究所机构知识库
Knowledge Management System of Institue of Mechanics, CAS
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微重力重点实验室 [10]
Creator
李宁 [10]
龙勉 [10]
吕东媛 [5]
吕守芹 [5]
孙树津 [4]
李培文 [3]
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Creator:李宁
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Creator:龙勉
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Mechanotransduction of liver sinusoidal endothelial cells under varied mechanical stimuli
期刊论文
ACTA MECHANICA SINICA, 2021, 页码: 17
Authors:
Shu XY(舒芯钰)
;
Li N(李宁)
;
Wu Y(武亿)
;
Li W(李旺)
;
Zhang XY(张晓宇)
;
Li PW(李培文)
;
Lv DY(吕东媛)
;
Lv SQ(吕守芹)
;
Long M(龙勉)
Adobe PDF(1359Kb)
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  |  
Submit date:2021/05/06
Liver sinusoidal endothelial cell
Shear stress
Mechanical stretch
Extracellular matrix
Stiffness
Characterizing liver sinusoidal endothelial cell fenestrae on soft substrates upon AFM imaging and deep learning
期刊论文
BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS, 2020, 卷号: 1864, 期号: 12, 页码: 9
Authors:
Li PW(李培文)
;
Zhou J(周瑾)
;
Li W(李旺)
;
Wu H(吴欢)
;
Hu JR(胡锦荣)
;
Ding QH(丁奇寒)
;
Lv SQ(吕守芹)
;
Pan J
;
Zhang CY
;
Li N(李宁)
;
Long M(龙勉)
Adobe PDF(4976Kb)
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View/Download:674/383
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Submit date:2020/11/30
Liver sinusoidal endothelial cells
Fenestrae
Atomic force microscopy
Imaging recognition
Fully convolutional networks
Substrate stiffness
Matrix stiffness and shear stresses modulate hepatocyte functions in a fibrotic liver sinusoidal model
期刊论文
AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY, 2020, 卷号: 320, 期号: 3, 页码: G272-G282
Authors:
Li W(李旺)
;
Li PW(李培文)
;
Li N(李宁)
;
Du Y(杜宇)
;
Lv SQ(吕守芹)
;
Elad, David
;
Long M(龙勉)
Adobe PDF(2812Kb)
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  |  
Submit date:2022/10/25
hepatocytes
liver fibrosis
matrix stiffness
shear flow
three-dimensional liver sinusoidal model
Cell Growth and Differentiation Under Microgravity
图书章节
2019
Authors:
Sun SJ(孙树津)
;
Wang CZ(王成之)
;
Li N(李宁)
;
Lv DY(吕东媛)
;
Chen Q(陈琴)
;
Long M(龙勉)
View
  |  
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View/Download:190/40
  |  
Submit date:2019/12/26
Microgravity-induced hepatogenic differentiation of rBMSCs on board the SJ-10 satellite
期刊论文
FASEB JOURNAL, 2019, 卷号: 33, 期号: 3, 页码: 4273-4286
Authors:
Lv DY(吕东媛)
;
Sun SJ(孙树津)
;
Zhang F(张帆)
;
Luo CH(罗春花)
;
Zheng L
;
Wu Y(武毅)
;
Li N(李宁)
;
Zhang C
;
Wang CZ
;
Chen Q
;
Long M(龙勉)
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  |  
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  |  
Submit date:2019/04/11
mesenchymal stem cells
mechanotransduction
hepatocyte
signaling pathway
Binding of intercellular adhesion molecule 1 to beta(2)-integrin regulates distinct cell adhesion processes on hepatic and cerebral endothelium
期刊论文
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY, 2018, 卷号: 315, 期号: 3, 页码: C409-C421
Authors:
Tong CF(佟春芳)
;
Zhang Y(章燕)
;
Lv SQ(吕守芹)
;
Li N(李宁)
;
Gong YX(龚一心)
;
Yang H
;
Feng SL
;
Du Y
;
Huang DD
;
Long M(龙勉)
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  |  
Adobe PDF(1593Kb)
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View/Download:566/275
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Submit date:2018/10/30
brain
ICAM-1
integrin
kinetics
liver
Microgravity-Induced Alterations of Inflammation-Related Mechanotransduction in Endothelial Cells on Board SJ-10 Satellite
期刊论文
FRONTIERS IN PHYSIOLOGY, 2018, 卷号: 9, 页码: 1025
Authors:
Li N(李宁)
;
Wang CZ(王成之)
;
Sun SJ(孙树津)
;
Zhang C(张晨)
;
Lv DY(吕东媛)
;
Chen Q(陈琴)
;
Long M(龙勉)
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  |  
Adobe PDF(3456Kb)
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View/Download:615/420
  |  
Submit date:2018/10/19
Microgravity
Sj-10 Satellite
Endothelial Cells
Adhesive Molecules
Cytoskeleton
Mechanotransduction
Nitric Oxide
Exosome Rna
Liver sinusoid on a chip
期刊论文
MICROFLUIDICS IN CELL BIOLOGY, PT A: MICROFLUIDICS FOR MULTICELLULAR SYSTEMS, 2018, 卷号: 146, 页码: 105-134
Authors:
Du Y(杜宇)
;
Li N(李宁)
;
Long M(龙勉)
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Adobe PDF(3794Kb)
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View/Download:551/274
  |  
Submit date:2019/05/30
Mechanical remodeling of normally sized mammalian cells under a gravity vector
期刊论文
FASEB JOURNAL, 2017, 卷号: 31, 期号: 2, 页码: 802-813
Authors:
Zhang C
;
Zhou LW(周吕文)
;
Zhang F(张帆)
;
Lv DY(吕东媛)
;
Li N(李宁)
;
Zheng L
;
Xu YH(徐艳红)
;
Li Z
;
Sun SJ(孙树津)
;
Long M(龙勉)
;
Long, M (reprint author), Chinese Acad Sci, Inst Mech, 15 North 4th Ring Rd, Beijing 100190, Peoples R China.
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Submit date:2017/07/24
Gravity-directed
Mechanosensing
Nucleus Translocation
Cytoskeletal Remodeling
Fac Reorganization
Mimicking liver sinusoidal structures and functions using a 3D-configured microfluidic chip
期刊论文
LAB ON A CHIP, 2017, 卷号: 17, 期号: 5, 页码: 782-794
Authors:
Du Y(杜宇)
;
Li N(李宁)
;
Yang H(杨浩)
;
Luo CH(罗春花)
;
Gong YX
;
Tong CF(佟春芳)
;
Gao YX(高宇新)
;
Lv SQ(吕守芹)
;
Long M(龙勉)
;
Long, M (reprint author), Chinese Acad Sci, Key Lab Micrograv, Natl Micrograv Lab, Ctr Biomech & Bioengn, Beijing 100190, Peoples R China.
;
Long, M (reprint author), Chinese Acad Sci, Beijing Key Lab Engn Construct & Mech, Inst Mech, Beijing 100190, Peoples R China.
;
Long, M (reprint author), Univ Chinese Acad Sci, Sch Engn Sci, Beijing 100049, Peoples R China.
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Submit date:2017/07/24