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Characterizing liver sinusoidal endothelial cell fenestrae on soft substrates upon AFM imaging and deep learning 期刊论文
BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS, 2020, 卷号: 1864, 期号: 12, 页码: 9
Authors:  Li PW(李培文);  Zhou J(周瑾);  Li W(李旺);  Wu H(吴欢);  Hu JR(胡锦荣);  Ding QH(丁奇寒);  Lv SQ(吕守芹);  Pan J;  Zhang CY;  Li N(李宁);  Long M(龙勉)
Adobe PDF(4976Kb)  |  Favorite  |  View/Download:701/391  |  Submit date:2020/11/30
Liver sinusoidal endothelial cells  Fenestrae  Atomic force microscopy  Imaging recognition  Fully convolutional networks  Substrate stiffness  
Cells' Flow and Immune Cell Priming under alternating g-forces in Parabolic Flight 期刊论文
SCIENTIFIC REPORTS, 2019, 卷号: 9, 页码: 11
Authors:  Moser D;  Sun SJ(孙树津);  Li N(李宁);  Biere K;  Hoerl M;  Matzel S;  Feuerecker M;  Buchheim JI;  Strewe C;  Thiel CS;  Gao YX(高宇欣);  Wang CZ(王成之);  Ullrich O;  Long M(龙勉);  Chouker A
View  |  Adobe PDF(2234Kb)  |  Favorite  |  View/Download:214/45  |  Submit date:2019/09/10
Impact of real-time shedding on binding kinetics of membrane-remaining L-selectin to PSGL-1 期刊论文
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY, 2019, 卷号: 316, 期号: 5, 页码: C678-C689
Authors:  Peng S(彭爽);  Chen SB(陈深宝);  Li LD(李林达);  Tong CF(佟春芳);  Li N(李宁);  Lv SQ(吕守芹);  Long M(龙勉)
View  |  Adobe PDF(2200Kb)  |  Favorite  |  View/Download:416/212  |  Submit date:2019/12/02
binding kinetics  competitive binding  L-selectin  modeling  real-time shedding  
Microgravity-induced hepatogenic differentiation of rBMSCs on board the SJ-10 satellite 期刊论文
FASEB JOURNAL, 2019, 卷号: 33, 期号: 3, 页码: 4273-4286
Authors:  Lv DY(吕东媛);  Sun SJ(孙树津);  Zhang F(张帆);  Luo CH(罗春花);  Zheng L;  Wu Y(武毅);  Li N(李宁);  Zhang C;  Wang CZ;  Chen Q;  Long M(龙勉)
View  |  Adobe PDF(3477Kb)  |  Favorite  |  View/Download:324/101  |  Submit date:2019/04/11
mesenchymal stem cells  mechanotransduction  hepatocyte  signaling pathway  
Binding of intercellular adhesion molecule 1 to beta(2)-integrin regulates distinct cell adhesion processes on hepatic and cerebral endothelium 期刊论文
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY, 2018, 卷号: 315, 期号: 3, 页码: C409-C421
Authors:  Tong CF(佟春芳);  Zhang Y(章燕);  Lv SQ(吕守芹);  Li N(李宁);  Gong YX(龚一心);  Yang H;  Feng SL;  Du Y;  Huang DD;  Long M(龙勉)
View  |  Adobe PDF(1593Kb)  |  Favorite  |  View/Download:583/281  |  Submit date:2018/10/30
brain  ICAM-1  integrin  kinetics  liver  
Liver sinusoid on a chip 期刊论文
MICROFLUIDICS IN CELL BIOLOGY, PT A: MICROFLUIDICS FOR MULTICELLULAR SYSTEMS, 2018, 卷号: 146, 页码: 105-134
Authors:  Du Y(杜宇);  Li N(李宁);  Long M(龙勉)
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Salt bridge interactions within the beta(2) integrin alpha(7) helix mediate force-induced binding and shear resistance ability 期刊论文
FEBS JOURNAL, 2018, 卷号: 285, 期号: 2, 页码: 261-274
Authors:  Zhang X(张潇);  Li LD;  Li N(李宁);  Shu XY;  Zhou LW(周吕文);  Lv SQ(吕守芹);  Chen SB;  Mao DB;  Long M(龙勉)
View  |  Adobe PDF(2053Kb)  |  Favorite  |  View/Download:268/76  |  Submit date:2018/10/30
beta(2) integrin  allostery  conformational stability  force  salt bridge interaction  
Mechanical remodeling of normally sized mammalian cells under a gravity vector 期刊论文
FASEB JOURNAL, 2017, 卷号: 31, 期号: 2, 页码: 802-813
Authors:  Zhang C;  Zhou LW(周吕文);  Zhang F(张帆);  Lv DY(吕东媛);  Li N(李宁);  Zheng L;  Xu YH(徐艳红);  Li Z;  Sun SJ(孙树津);  Long M(龙勉);  Long, M (reprint author), Chinese Acad Sci, Inst Mech, 15 North 4th Ring Rd, Beijing 100190, Peoples R China.
View  |  Adobe PDF(3686Kb)  |  Favorite  |  View/Download:511/163  |  Submit date:2017/07/24
Gravity-directed  Mechanosensing  Nucleus Translocation  Cytoskeletal Remodeling  Fac Reorganization  
Mimicking liver sinusoidal structures and functions using a 3D-configured microfluidic chip 期刊论文
LAB ON A CHIP, 2017, 卷号: 17, 期号: 5, 页码: 782-794
Authors:  Du Y(杜宇);  Li N(李宁);  Yang H(杨浩);  Luo CH(罗春花);  Gong YX;  Tong CF(佟春芳);  Gao YX(高宇新);  Lv SQ(吕守芹);  Long M(龙勉);  Long, M (reprint author), Chinese Acad Sci, Key Lab Micrograv, Natl Micrograv Lab, Ctr Biomech & Bioengn, Beijing 100190, Peoples R China.;  Long, M (reprint author), Chinese Acad Sci, Beijing Key Lab Engn Construct & Mech, Inst Mech, Beijing 100190, Peoples R China.;  Long, M (reprint author), Univ Chinese Acad Sci, Sch Engn Sci, Beijing 100049, Peoples R China.
View  |  Adobe PDF(6728Kb)  |  Favorite  |  View/Download:795/508  |  Submit date:2017/07/24
Effects of Simulated Microgravity on Functions of Neutrophil-like HL-60 Cells 期刊论文
MICROGRAVITY SCIENCE AND TECHNOLOGY, 2015, 卷号: 27, 期号: 6, 页码: 515-527
Authors:  Wang CZ(王成之);  Li N(李宁);  Zhang C(张晨);  Sun SJ(孙树津);  Gao YX(高宇欣);  Long M(龙勉);  Long, M (reprint author), Chinese Acad Sci, Inst Mech, Ctr Biomech & Bioengn, Key Lab Micrograv,Natl Micrograv Lab, Beijing 100190, Peoples R China.
View  |  Adobe PDF(1539Kb)  |  Favorite  |  View/Download:332/97  |  Submit date:2016/01/08
Hl-60  Pmn  Effects Of Simulated Microgravity  Rccs  Flow Chamber